Examples

Below are the FTMove results for 22 proteins with known allosteric binding sites.


Protein PDB ID and Chain ID Domain Splitting Pymol Session Structure Binding Site Strengths Clustered Heatmap
DAHP Synthase 1GG1_A False PSE CSV PNG
PDK1 1H1W_A True PSE CSV PNG
Fructose 1,6-bisphosphate 2FBP_A False PSE CSV PNG
Glycogen Phosphorylase 1BX3_A True PSE CSV PNG
p38 Alpha Kinase 1WBO_A False PSE CSV PNG
MEK1 3EQI_A True PSE CSV PNG
Glucokinase 3IDH_A False PSE CSV PNG
Kinesin 3HQD_A False PSE CSV PNG
PTP1B 2F70_A False PSE CSV PNG
TEM-1 beta-lactamase 1JWP_A False PSE CSV PNG
CHK1 2E9N_A True PSE CSV PNG
ABL1 2G2I_A True PSE CSV PNG
SRC 3F6X_A False PSE CSV PNG
Tryptophan-tRNA ligase 1D2R_A False PSE CSV PNG
Acetylcholinesterase 1AMN_A False PSE CSV PNG
Insulin Growth Factor-1 Receptor 1JQH_A False PSE CSV PNG
B-RAF 4H58_B False PSE CSV PNG
Monoamine Oxidase B 1GOS_A False PSE CSV PNG
PDK2 5J71_A True PSE CSV PNG
Glutamate Racemase 2JFY_A False PSE CSV PNG
Farnesyl disphosphate synthase 4DEM_F False PSE CSV PNG
Androgen Receptor 2AM9_A False PSE CSV PNG



FTMove should only be used for noncommercial purposes.
Vajda Lab (Boston University).